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Study details
Enrolling now

Neutralizing Interleukin (IL)-6

Icahn School of Medicine at Mount Sinai
NCT IDNCT07493317ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Ages

18–70

Locations

1 site in NY

What this study is about

This Phase 2 study is testing Tocilizumab in people with depression.

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

tocilizumab (Monoclonal antibody; blocks IL-6 receptor to reduce inflammation)

Drug routes

infusion

Endpoints

Secondary: Change in Montgomery-Asberg Depression Rating Scale (MADRS)

Body systems

Psychiatry / Mental Health