Efficacy and Safety of Eloralintide in People With Osteoarthritis Knee Pain and Obesity or Overweight
Phase 3
900
about 2.3 years
18+
34 sites in AL, AZ, CA +12
What this study is about
This trial is testing a treatment called Eloralintide to see if it helps people with osteoarthritis knee pain who are also overweight or obese. The trial will last about 75 weeks, including screening.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Eloralintide
- 2.Take Placebo
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Change from Baseline in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale Score, Percent Change from Baseline in Body Weight
Secondary: Achievement of Improved Categorical Shift in Patient Global Impression of Severity (PGIS) - Target Knee Pain, Change from Baseline WOMAC Pain Subscale Score, Change from Baseline in Average Pain Intensity Numeric Rating Scale (API-NRS) Score, Change from Baseline in Body Mass Index (BMI), Change from Baseline in Distance Walked During the 6-Minute Walk Test, Change from Baseline in Health Status EQ-5D-5L Health State Utility, Change from Baseline in SF-36v2 Acute Form Domain Scores With Exception of the Physical Functioning Domain Score, Change from Baseline in Short Form-36 (SF-36 v2) Acute Form Physical Functioning Domain Score
Endocrinology, Musculoskeletal