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Study details
Enrolling now

Efficacy of Methylprednisolone for Pain Control After ACL Repair

St. Louis University
NCT IDNCT07158476ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

90

Study length

about 5.9 years

Ages

13–50

Locations

1 site in MO

What this study is about

Researchers are testing whether adding a methylprednisolone taper to the pain regimen after ACL repair surgery reduces postoperative pain and opioid use without increasing complications. The trial will involve adults and children undergoing ACL repair surgery and comparing their pain levels and opioid usage with those who receive standard pain management.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Gabapentin 300 mg
  • 2.Take Hydrocodone 5Mg/Acetaminophen 325Mg Tab
  • 3.Take Ketorolac 10 Mg Oral Tablet
  • +2 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralOral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

analgesic (Reduces fever and pain (mechanism not fully understood)), gabapentin (Modulates calcium channels; used for neuropathic pain and seizures), hydrocodone, ketorolac, meloxicam

Drug routes

oral, oral (Oral Tablet), injection, intravenous

Endpoints

Primary: Numerical Rating Scale (NRS) pain scores