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Study details
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Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain

Wake Forest University Health Sciences
NCT IDNCT07053774ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

24

Study length

about 11 months

Ages

18–75

Locations

1 site in NC

What this study is about

Researchers are testing whether oxytocin helps reduce pain from heat. Participants will receive oxytocin or a placebo through the nose or vein, and rate their pain levels after each treatment. The trial will last about 329 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Intravenous oxytocin
  • 2.Receive Intravenous placebo
  • 3.Take Intranasal oxytocin
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
intranasalintranasal

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

oxytocin (Hormone; causes uterine contractions)

Drug routes

intranasal, infusion

Endpoints

Primary: Pain Scale Score - During Skin Heating, Pain Scale Score - End of 5-minute Skin Heating

Secondary: Pain Scale Score - During Skin Heating