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Study details
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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

AbbVie
NCT IDNCT06972446ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

180

Study length

about 2.4 years

Ages

18+

Locations

38 sites in AZ, CA, CO +11

What this study is about

Researchers are testing different treatments for moderately to severely active rheumatoid arthritis. The trial will evaluate the efficacy and safety of lutikizumab, ravagalimab, or a combination of both compared to placebo. Participants will attend regular visits during it at a hospital or clinic.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Lutikizumab
  • 2.Take Placebo
  • 3.Take Ravagalimab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

monoclonal antibody

Endpoints

Primary: Number of Participants with Adverse Events (AEs)

Secondary: Change from Baseline in DAS28 (CRP), Percentage Of Participants Achieving CR per CDAI, Percentage Of Participants Achieving Clinical Remission (CR) per DAS28 (CRP), Percentage Of Participants Achieving Low Disease Activity (LDA) per Disease Activity Score-28 With C-Reactive Protein (DAS28-CRP)

Body systems

Immune