Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
200
about 2.6 years
8–17
1 site in NY
What this study is about
Researchers are testing different treatment components to improve pediatric post-traumatic stress disorder (PTSD). The trial will also provide evidence on how these components work. Researchers will compare the components to a psychological placebo and examine their effects alone and in combination with other components.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Participate in Bi-lateral Stimulation
- 2.Participate in Cognitive Processing
- 3.Participate in Emotion Regulation
- +2 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Mean Change in PTSD Symptoms - Child PTSD Symptom Scale for DSM-5 (CPSS), Mean Change in PTSD Symptoms - Child and Adolescent Trauma Screen (CATS-2), Mean Change in PTSD Symptoms - Clinician Administered PTSD Scale for DSM-5 - Child/Adolescent Version (CAPS-CA)
Secondary: Brain Aging - Magnetic Resonance Imaging (MRI), Change in Network Connectivity - Magnetic Resonance Imaging (MRI), Change in Neural Structure - Magnetic Resonance Imaging (MRI), Change in PTSD Symptom Trajectories - Child PTSD Symptom Scale for DSM-5 (CPSS), Change in PTSD Symptom Trajectories - Child and Adolescent Trauma Screen (CATS-2), Change in PTSD, Mood, Anxiety, and Disruptive Behavior Disorder Symptom Trajectories - Ecological Momentary Assessment (EMA), Changes in Trajectories of C-Reactive Protein (CRP), Changes in Trajectories of Interleukin-6 (IL-6)
therapy
Psychiatry / Mental Health, Oncology