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Study details
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A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Hoffmann-La Roche
NCT IDNCT06863961ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

160

Study length

about 1.7 years

Ages

18+

Locations

25 sites in CA, FL, GA +12

What this study is about

Researchers are testing a treatment called Afimkibart (also known as RO7790121) for people with moderate to severe atopic dermatitis. The trial will last 604 days and involve approximately 160 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Afimkibart
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Change from Baseline in Dermatology Quality of Life Index at Week 16, Week 32 and by Visit, Percent Change from Baseline in EASI by Visit, Percent Change from Baseline in Peak Pruritus Numerical Rating Scale (NRS) Score by Visit, Percentage of Participants with Adverse Events

Body systems

Dermatology