Study details
Enrolling now
Anxiety During Abstinence in Alcohol Use Disorder
Columbia University
NCT IDNCT06793488ClinicalTrials.gov data as of Apr 2026
Phase
EARLY_PHASE1
Target enrollment
60
Study length
about 4 years
Ages
21–55
Locations
1 site in NY
What this study is about
This trial is testing how anxiety changes during abstinence in people with alcohol use disorder (AUD). Researchers will give some participants disulfiram to help them stay abstinent and scan their brains using fMRI. They are also comparing this to healthy volunteers who do not receive disulfiram.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Disulfiram 250 mg
- 2.Undergo functional MRI
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Oral
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
disulfiram
Drug routes
oral (Oral Tablet)
Procedures
imaging
Body systems
Psychiatry / Mental Health