Study details
Enrolling now
Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)
The University of Texas Health Science Center, Houston
NCT IDNCT06706258ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
400
Study length
about 2.4 years
Ages
18–90
Locations
1 site in TX
What this study is about
Researchers are testing if giving pantoprazole or famotidine to patients after heart surgery can help prevent acute kidney injury. The trial will last for 888 days and involve approximately 400 adult patients undergoing cardiac surgery requiring cardiopulmonary bypass.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Pepcid (Famotidine) 20 mg q 12 hrs for 3 days
- 2.Take Protonix (Pantoprazole) 40 mg q 12 hrs for 3 days
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
OralOral
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
famotidine, pantoprazole
Drug routes
oral (Oral Tablet), oral (Delayed Release Oral Tablet)
Body systems
Renal