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Study details
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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

PPD Development, LP
NCT IDNCT06701669ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

200

Study length

about 3.3 years

Ages

18+

Locations

36 sites in AL, CA, CO +20

What this study is about

Researchers are testing a treatment called paridiprubart in adults with Acute Respiratory Distress Syndrome (ARDS). Participants will be randomly assigned to receive either paridiprubart or a placebo. The trial will last 1208 days and involve approximately 200 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Cohort B: paridiprubart
  • 2.Take Cohort B: placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Days of hospitalization up to and including Day 28, Improvements in oxygenation measured as change from baseline in PaO2/FiO2 ratio up to and including Day 28 (or discharge, whichever is earlier), Incidence and severity of adverse events (AEs) /adverse event of special interest (AESI) / serious adverse event (SAEs)