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Study details
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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

PPD Development, LP
NCT IDNCT06701656ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

200

Study length

about 2.9 years

Ages

18+

Locations

36 sites in AL, CA, CO +20

What this study is about

This trial is testing a treatment called bevacizumab in adults with Acute Respiratory Distress Syndrome (ARDS). Participants will either receive bevacizumab or a placebo. It lasts 1068 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Cohort C: bevacizumab
  • 2.Take Cohort C: placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

bevacizumab

Drug routes

infusion

Endpoints

Secondary: Days of hospitalization up to and including Day 28, Improvements in oxygenation measured as change from baseline in PaO2/FiO2 ratio up to and including Day 28 (or discharge, whichever is earlier), Incidence and severity of adverse events (AEs) /adverse event of special interest (AESI) / serious adverse event (SAEs)