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Study details
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A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

Eli Lilly and Company
NCT IDNCT06672939ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

125

Study length

about 2.4 years

Ages

12–17

Locations

15 sites in CA, CT, GA +9

What this study is about

Researchers are testing a treatment called orforglipron versus a placebo in adolescents with obesity or overweight and related health problems. The trial will last about 18 months.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Orforglipron
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Percent Change from Baseline in Body Mass Index (BMI)

Secondary: Change from Baseline in BMI, Change from Baseline in Body Weight, Change from Baseline in Body Weight Percentile, Change from Baseline in Diastolic Blood Pressure, Change from Baseline in Fasting Glucose, Change from Baseline in Systolic Blood Pressure, Change from Baseline in Waist Circumference, Change in Impact of Weight on Quality of Life (IWQOL)-Kids Total and Domain Scores

Body systems

Endocrinology