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Study details
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Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

ONL Therapeutics
NCT IDNCT06659445ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

324

Study length

about 3.1 years

Ages

55+

Locations

27 sites in AZ, CA, CO +14

What this study is about

This trial is testing a treatment called ONL1204 for people with geographic atrophy (GA) linked to age-related macular degeneration (AMD). The goal is to see if this treatment helps improve vision and is safe.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Avacincaptad Pegol intravitreal solution
  • 2.Sham
  • 3.Take ONL1204 Opthalmic solution

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVintravitreal

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

avacincaptad pegol

Drug routes

injection, intravitreal

Endpoints

Primary: Primary Endpoint