Study details
Enrolling now
Diclofenac Dose Response Study
University of Maryland, Baltimore
NCT IDNCT06636227ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
24
Study length
about 1.7 years
Ages
21–65
Locations
1 site in MD
What this study is about
This trial is testing whether different doses of diclofenac can increase KYNA levels in people with alcohol use disorder. Participants will receive either diclofenac or a placebo for four sessions, and researchers will measure KYNA and QUIN levels, as well as craving and mood.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Diclofenac 100mg
- 2.Take Diclofenac 50mg
- 3.Take Diclofenac 75mg
- +1 more
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Oral
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
diclofenac
Drug routes
oral (Oral Capsule)
Body systems
Psychiatry / Mental Health