Study details
Enrolling now
Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism
University of Pennsylvania
NCT IDNCT06559995ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2/3
Target enrollment
30
Study length
about 2.4 years
Ages
18–65
Locations
1 site in PA
What this study is about
This trial is testing whether a ketone supplement helps with alcohol withdrawal symptoms in adults with moderate to severe alcohol use disorder. Participants will receive either a ketone supplement or a placebo beverage, along with a magnetic resonance imaging session. It lasts for 882 days.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Participate in magnetic resonance imaging session
- 2.Placebo beverage
- 3.Ketone supplement D-beta-hydroxybutryric acid and R-1,3 butanediol 12g of ketones,
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
dietary supplement
Procedures
imaging
Body systems
Psychiatry / Mental Health