Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients
Phase 2/3
100
about 11 months
18+
1 site in TX
What this study is about
Researchers are testing whether starting a proton pump inhibitor (PPI) medication early after an injury can help prevent acute kidney injury (AKI) in people who have experienced hemorrhagic shock. The trial will compare this approach to the usual way of starting PPIs, which is later on. Kidney injury will be assessed by measuring specific biomarkers in urine and tracking the incidence, severity, and AKI-free days within the first week, as well as major adverse kidney events (MAKE) at day 30.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days
- 2.Take Protonix (pantoprazole) 40 mg q 24 hrs for 2 days
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
pantoprazole
oral (Delayed Release Oral Tablet)
Primary: Urinary Kidney Biomarker Levels
Renal