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Study details
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Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)

University of Southern California
NCT IDNCT06515782ClinicalTrials.gov data as of Apr 2026
Target enrollment

50

Study length

about 2 years

Ages

18–55

Locations

1 site in CA

What this study is about

Researchers are testing if a fasting mimicking diet improves the quality of life for people with relapsing multiple sclerosis who are already taking disease-modifying therapies. The trial will compare this to a Mediterranean diet control group.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Health-related Quality of Life (HRQOL)

Secondary: Assessing Safety and Tolerability of a FMD in MS: Compliance and Serious Adverse Events, To evaluate alterations in immune function by assessing changes in cell counts, serum cytokines and secretion patterns, with a focus on pro-inflammatory cytokines IL-2, interferon-gamma (IFNγ), and IL-17A, and the regulatory cytokine, IL-10. Units: pg/mL, To evaluate the effect on clinical measures of neurological status: EDSS

Body systems

Neurology