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Study details
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Empagliflozin Trial to Reduce Arterial Stiffness in Older Adults

University of Missouri-Columbia
NCT IDNCT06506422ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2/3

Target enrollment

80

Study length

about 4.5 years

Ages

60–80

Locations

1 site in MO

What this study is about

Researchers are testing whether empagliflozin, a medication, can help reduce arterial stiffness in older adults. The trial involves randomly assigning participants aged 60-80 to either empagliflozin or a placebo for 12 weeks. It will last approximately 1655 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Empagliflozin 10 MG
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

empagliflozin (SGLT2 inhibitor; increases glucose excretion in urine)

Endpoints

Primary: Carotid Femoral Pulse Wave Velocity (cfPWV)