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Study details
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Precision Administration of Anti-thymocyte Globulin With or Without Verapamil

University of Florida
NCT IDNCT06455319ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

60

Study length

about 4.8 years

Ages

6–35

Locations

2 sites in CO, FL

What this study is about

This trial is testing a new way to treat type 1 diabetes. It involves using anti-thymocyte globulin (ATG) with or without verapamil, and it aims to improve how well the treatment works for each person. The goal is to find better ways to manage type 1 diabetes by understanding what makes people respond differently to the treatment.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Anti-thymocyte globulin (ATG)
  • 2.Take Placebo
  • 3.Take verapamil extended release capsule

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

verapamil (Calcium channel blocker; slows heart rate and dilates vessels)

Drug routes

oral

Endpoints

Primary: AUC C-peptide between ATG and placebo values, Change in 2-hr MMTT AUC C-peptide

Body systems

Endocrinology