Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
Phase 4
100
about 4.7 years
18–60
1 site in OR
What this study is about
This trial is testing whether trauma affects emotion regulation, inflammation, and brain function differently between men and women with alcohol use disorder. It aims to determine how naltrexone impacts these factors and its effectiveness in reducing alcohol cravings and promoting abstinence in both sexes.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Naltrexone
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
naltrexone
injection, intramuscular
Primary: Change from baseline in alcohol use (number of drinking days, amount used per day)
Secondary: Change from baseline in craving (include craving measures/questionnaires), Change from baseline in neuropsychological testing scores
Psychiatry / Mental Health