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Study details
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Psilocybin or Ketamine for Alcohol Use Disorder

University of Iowa
NCT IDNCT06405607ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

80

Study length

about 2.9 years

Ages

21–65

Locations

1 site in IA

What this study is about

Researchers are testing whether psilocybin or ketamine can help people with alcohol use disorder. The trial will involve two groups: one group will receive psilocybin, and another group will receive ketamine, both along with therapy.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Ketamine
  • 2.Take Psilocybin

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ketamine (NMDA receptor antagonist; induces dissociative anesthesia and analgesia)

Drug routes

oral

Body systems

Psychiatry / Mental Health