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Study details
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Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

VA Office of Research and Development
NCT IDNCT06399653ClinicalTrials.gov data as of Apr 2026
Target enrollment

80

Study length

about 4.7 years

Ages

21–65

Locations

1 site in CA

What this study is about

This trial is testing a new treatment for alcohol use disorder (AUD) that uses non-invasive vagus nerve stimulation. The goal is to see if this treatment can improve how well veterans with AUD function and their quality of life.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use Cervical transcutaneous vagus nerve stimulation (active comparator)
  • 2.Use Cervical transcutaneous vagus nerve stimulation (sham comparator)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Hamilton Anxiety Rating Scale (HAM-A), WHO Quality of Life assessment (WHOQOL-BREF)

Secondary: Neural response to heat pain fMRI task

Devices

therapeutic

Body systems

Psychiatry / Mental Health