Skip to content
Study details
Enrolling now

Nebulized Ketamine vs. Nebulized Fentanyl for Acute Pain

Antonios Likourezos
NCT IDNCT06364540ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

150

Study length

about 2.7 years

Ages

18–120

Locations

1 site in NY

What this study is about

Researchers are testing whether nebulized ketamine or nebulized fentanyl is better at relieving acute pain in the emergency department. The trial will compare a 0.75 mg/kg dose of ketamine administered via breath-actuated nebulizer (BAN) to a 3 mcg/kg dose of fentanyl administered via breath-actuated nebulizer (BAN).

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Fentanyl
  • 2.Take Ketamine

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

fentanyl, ketamine (NMDA receptor antagonist; induces dissociative anesthesia and analgesia)

Drug routes

oral (Oral Lozenge)

Endpoints

Primary: Reduction of pain scores on the numeric rating pain scale (NRS)

Secondary: Severity of Adverse Events