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Study details
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Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

University of Colorado, Denver
NCT IDNCT06349577ClinicalTrials.gov data as of Apr 2026
Target enrollment

1,100

Study length

about 3.5 years

Ages

18–85

Locations

1 site in CO

What this study is about

This trial is testing whether pulsatile blood flow during cardiopulmonary bypass can reduce acute kidney injury after cardiac surgery. Investigators will also evaluate the safety and impact of pulsatile flow on clinical outcomes compared to non-pulsatile flow during cardiopulmonary bypass.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Non-pulsatile blood flow
  • 2.Pulsatile blood flow

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: 30-day mortality

Body systems

Renal