Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
Phase 4
40
about 4.9 years
18–55
2 sites in GA, NY
What this study is about
Researchers are testing whether concentrated bone marrow aspirate (cBMA) can improve symptoms of post-traumatic osteoarthritis (PTOA) after revision anterior cruciate ligament reconstruction surgery. The trial will examine if cBMA injection leads to better pain relief, changes in inflammatory markers, and understand the cellular components that may contribute to its effects.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Concentrated Bone Marrow Aspirate Injection
- 2.Undergo Revision Anterior Cruciate Ligament Reconstruction
- 3.Undergo Sham Incision
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
injection
Primary: Change from baseline in patient reported knee pain
Secondary: Change from baseline in articular cartilage relative proteoglycan content and collagen fibril organization, Change from baseline in cartilage morphology
Musculoskeletal