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Study details
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Studying TAK-243 in Patients With Advanced Cancer

National Cancer Institute (NCI)
NCT IDNCT06223542ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

95

Study length

about 1.1 years

Ages

18+

Locations

1 site in MD

What this study is about

This trial is testing the safety and best dose of a drug called TAK-243 in people with advanced cancer. TAK-243 is an inhibitor that may help stop cancer cells from growing and surviving.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take UAE Inhibitor TAK-243
  • 2.Undergo Biopsy Procedure
  • 3.Undergo Biospecimen Collection
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Maximum tolerated dose (MTD), Recommended phase 2 dose

Secondary: Pharmacodynamic (PD) variables

Procedures

biopsy, diagnostic, imaging

Body systems

Oncology