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Study details
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Dynamic Treatment Regiments for Glucocorticoid Tapering

VA Office of Research and Development
NCT IDNCT06072768ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

200

Study length

about 7 years

Ages

18+

Locations

2 sites in MI

What this study is about

This trial is testing different ways to gradually reduce steroid medications (like prednisone) in people with rheumatoid arthritis. The goal is to understand why some people experience problems when the dose is lowered, while others don't. Researchers will look at various factors like inflammation levels and hormone balances to better understand these differences.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take 15-day taper prednisone
  • 2.Take 150-day taper prednisone

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

corticosteroid (Glucocorticoid; suppresses inflammation and immune response)

Drug routes

oral

Body systems

Immune