A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Phase 3
231
about 7 years
5–11
30 sites in AL, AR, AZ +12
What this study is about
This trial is testing a treatment called tezepelumab compared to a placebo (inactive pill) in children with severe asthma. The goal is to see if tezepelumab helps improve asthma control and is safe for this age group.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Placebo
- 2.Receive Tezepelumab
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
tezepelumab
Secondary: Change from baseline in Asthma Control Questionnaire - Interviewer Administered (ACQ-IA) score, Change from baseline in Paediatric Asthma Quality of Life Questionnaire (PAQLQ-(S)-IA) total score, Change from baseline in blood eosinophil count, Change from baseline in fractional exhaled nitric oxide (FeNO), Change from baseline in pre-bronchodilator (pre-BD) forced expiratory volume in 1 second (FEV1) percent predicted normal (PN), Change from baseline in pre-bronchodilator (pre-BD) peak expiratory flow (PEF), Change from baseline in total serum IgE, Change from baseline in weekly mean daily Paediatric Asthma Symptom Observer (PASO) score
Respiratory