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Study details
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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

Pfizer
NCT IDNCT05995964ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

340

Study length

about 3.3 years

Ages

18+

Locations

52 sites in AL, AZ, CA +16

What this study is about

Researchers are testing two trial medicines, PF-07275315 and PF-07264660, in people with moderate to severe atopic dermatitis. It is seeking participants who have confirmed atopic dermatitis for at least 6 months and are not having an effective treatment result from medicines that are applied on skin for AD. Participants will receive either PF-07275315 or PF-07264660 or placebo as multiple shots in the clinic over the course of each Stage.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo
  • 2.Take PF-07264660
  • 3.Take PF-07275315

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: The number and % of participants achieving a Percent change from baseline in EASI total score at scheduled time points, The number and % of participants with treatment emergent AEs

Body systems

Dermatology