Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage
Phase 1/2
30
about 3.5 years
0.000114079458624521–0.00205343025524138
1 site in OK
What this study is about
This trial is testing whether giving theophylline, a medication, to newborns who have experienced brain injury and are being cooled down can help prevent kidney damage. The goal of this pilot trial is to lay the groundwork for future studies that could potentially use theophylline to protect kidneys in many more infants at risk.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Repeat Dose Theophylline
- 2.Take Single Dose Theophylline
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
bronchodilator (Methylxanthine; relaxes airway smooth muscle (PDE inhibition)
oral (Extended Release Oral Capsule)
Secondary: Pharmacokinetic Profile of Theophylline#1, Pharmacokinetic Profile of Theophylline#2
Renal