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Study details
Enrolling now

AU409 for Advanced Liver Cancers or Solid Tumors

University of Southern California
NCT IDNCT05791448ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

36

Study length

about 4 years

Ages

18+

Locations

2 sites in CA

What this study is about

This trial is testing the safety, side effects, and best dose of a new intervention called AU409 in people with advanced liver cancers or solid tumors that have spread to the liver. The goal is to see if AU409 can stop cancer from growing and spreading.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take RNA Transcription Modulator AU-409
  • 2.Undergo Biospecimen Collection
  • 3.Undergo Computed Tomography
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Incidence of adverse events, Maximum Tolerated Dose

Secondary: Pharmacokinetics evaluation - Peak plasma concentration (Cmax), Pharmacokinetics evaluation - Peak time (Tmax)

Procedures

diagnostic, imaging

Body systems

Oncology