Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure
20
about 2.8 years
18+
1 site in NY
What this study is about
This trial is testing if wearing a non-invasive breathing support device over the chest/abdomen improves markers of breathing in patients with lung injury requiring high-flow oxygen. The breathing support device consists of a plastic shell that sits over the chest and abdomen and connects to a vacuum that helps the chest expand with breathing. This breathing support is known as continuous negative external pressure (CNEP). Trial findings will help determine if this breathing support device might be useful for patients with acute hypoxemic respiratory failure (AHRF).
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Use HFNC + CNEP10
- 2.Use HFNC + CNEP20
- 3.Use HFNC + CNEP30
- +1 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Change from baseline in SpO2/FiO2
Secondary: Change from baseline in Blood Pressure, Change from baseline in Breathing Discomfort, Change from baseline in Heart Rate, Change from baseline in Lightheadedness, Change from baseline in Nausea, Change from baseline in ROX Index, Change from baseline in Respiratory Rate, Change from baseline in Skin Discomfort