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Study details
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Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

Wei-Che Ko
NCT IDNCT05535738ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2/3

Target enrollment

45

Study length

about 5.1 years

Ages

18+

Locations

1 site in MA

What this study is about

This trial is testing how different treatments affect skin inflammation in people with allergic contact dermatitis. It uses a model of skin inflammation and biologic medications like adalimumab, betamethasone valerate, canakinumab, dupilumab, fluticasone propionate, guselkumab, sarilumab, ustekinumab, and triamcinolone acetonide to understand how these treatments work in the skin.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Adalimumab
  • 2.Take Betamethasone Valerate
  • 3.Take Canakinumab
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVOral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

adalimumab (Monoclonal antibody; blocks TNF-alpha to reduce inflammation), Antineoplastic Agent [TC] (Corticosteroid Hormone Receptor Agonists), canakinumab, dupilumab, Respiratory System Agent (Corticosteroid Hormone Receptor Agonists), guselkumab, sarilumab, Anti-inflammatory Agent (Corticosteroid Hormone Receptor Agonists)

Drug routes

injection, oral (Oral Tablet), subcutaneous, topical (Topical Lotion), intravenous, injection (Injection)

Procedures

biopsy

Body systems

Dermatology