Combination Therapy for Sleep Disturbance in Patients With Advanced Cancer
Phase 2/3
188
about 4.3 years
18+
1 site in TX
What this study is about
This trial is testing if a combination of treatments, including melatonin, methylphenidate, and/or bright light therapy (BLT), can improve sleep and related symptoms like fatigue, anxiety, and depression in people with advanced cancer. This is an investigational trial comparing these treatments to placebos.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Placebo for Melatonin
- 2.Take Melatonin
- 3.Take Methylphenidate
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
melatonin (Hormone supplement; regulates sleep-wake cycle), methylphenidate (CNS stimulant; blocks reuptake of dopamine and norepinephrine)
oral (Disintegrating Oral Tablet)
Primary: Pittsburgh Sleep Quality Index (PSQI) questionnaires
Psychiatry / Mental Health, Oncology