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Study details
Enrolling now

Treat-to-Target Endoscopic Remission in IBD Patients

University of California, San Diego
NCT IDNCT05230173ClinicalTrials.gov data as of Apr 2026
Target enrollment

250

Study length

about 5.7 years

Ages

18+

Locations

22 sites in CA, CO, CT +12

What this study is about

This trial is testing whether switching to a different targeted immunomodulator (TIM) therapy, aiming for endoscopic remission, is more effective than continuing the current TIM in people with inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, who are currently in symptomatic remission but have moderate to severe inflammation on endoscopy.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Pragmatic

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Time to Treatment Failure

Secondary: Overall Quality of Life

Body systems

Gastroenterology