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Study details
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Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer

Roberto Vargas
NCT IDNCT05065736ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

4

Study length

about 3.3 years

Ages

18+

Locations

1 site in OH

What this study is about

This trial is testing whether a new imaging agent called 18F-Clofarabine (CFA) can be used to image cancer metabolism. The goal is to see if CFA can measure deoxycytidine kinase activity, which helps determine how well certain cancer drugs are taken up by cancer cells.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take 18F-Clofarabine

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Drug routes

injection (Injection)

Endpoints

Primary: Evaluate CFA as a PET imaging agent

Secondary: Adverse Events, Correlate CFA uptake with OS, Correlate CFA uptake with PFS, Correlate CFA uptake with conventional imaging

Body systems

Oncology