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Study details
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Twin Block, Pain Medications and Third Molar Extractions

Rutgers, The State University of New Jersey
NCT IDNCT04880707ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

48

Study length

about 2.5 years

Ages

18+

Locations

1 site in NJ

What this study is about

Researchers are testing whether a Twin block dental anesthetic injection can help manage pain after wisdom tooth removal. The trial will compare the Twin block to a placebo in patients experiencing significant jaw pain. Researchers will track pain levels and opioid usage over 7 days to see if the Twin block reduces pain and medication needs.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Twin block local anesthetic nerve block using standard dental anesthetic
  • 2.Twin block with placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Mean NRS pain score, Post-injection muscle pain