Study details
Enrolling now
NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial
Kaiser Permanente
NCT IDNCT04750616ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
304
Study length
about 3.8 years
Ages
18+
Locations
1 site in CA
What this study is about
This trial is testing whether niacinamide can help prevent myocardial injury after cardiac surgery. Patients will be randomly assigned to receive either niacinamide or a placebo.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Niacinamide
- 2.Take Placebo
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Oral
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
nicotinamide
Drug routes
oral (Oral Tablet)
Endpoints
Primary: Troponin T AUC
Secondary: Mean difference in eGFR, Mean difference in uQuin/Tryp ratio AUC
Body systems
Renal