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Study details
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ROX Index for Predicting Intubation Timing in Nasal High Flow

Hospital Universitari Vall d'Hebron Research Institute
NCT IDNCT04707729ClinicalTrials.gov data as of Apr 2026
Target enrollment

630

Study length

about 4.6 years

Ages

18–120

Locations

1 site in IL

What this study is about

This trial is testing if using the ROX index algorithm to predict when patients with acute hypoxemic respiratory failure need intubation, as supported by nasal high flow therapy, leads to earlier intubation compared to standard methods. The goal is to see if this approach improves patient outcomes.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.ROX index algorithm

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Hospital length of stay, Hospital mortality, ICU length of stay