MOCHA Trial: Montelukast After ACL Reconstruction
EARLY_PHASE1
30
about 6.4 years
25–50
1 site in KY
What this study is about
Researchers are testing whether taking montelukast, a medication, after an ACL reconstruction can reduce inflammation and slow down cartilage breakdown. The trial will involve adults who have had ACL surgery with meniscal tears or post-traumatic osteoarthritis. Participants will be randomly assigned to take either montelukast or a placebo for 6 months.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Montelukast
- 2.Take Placebo
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
montelukast (Leukotriene receptor antagonist; reduces inflammation in airways)
oral (Oral Tablet)
Primary: Knee injury and Osteoarthritis Outcome Score (KOOS), Shape of the medial femoral condyle on MRI, T1rho relaxation time on MRI