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Study details
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Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma

Gulam Manji
NCT IDNCT04543071ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

10

Study length

about 7.8 years

Ages

18+

Locations

3 sites in NY, RI, WI

What this study is about

This trial is testing a new treatment with cemiplimab, motixafortide, gemcitabine, and nab-paclitaxel for pancreatic adenocarcinoma. The goal is to see if this combination can shrink tumors, prolong life, and be safe for patients.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Cemiplimab
  • 2.Take Gemcitabine
  • 3.Take Motixafortide
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

cemiplimab, gemcitabine, motixafortide, paclitaxel (Taxane chemotherapy; stabilizes microtubules)

Drug routes

injection (Injection), injection, subcutaneous, infusion

Endpoints

Primary: Overall Response Rate (Complete Response (CR) + Partial Response (PR))

Secondary: Disease Control Rate, Median Overall Survival, Median Progression Free Survival

Body systems

Oncology