Limiting AAA With Metformin (LIMIT) Trial
Phase 2
314
about 6.3 years
50–95
1 site in CA
What this study is about
This trial is testing whether metformin, a medication, can help slow the growth of abdominal aortic aneurysms (AAAs). AAAs are abnormal enlargements of the aorta in the abdomen that carry a risk of rupture and life-threatening bleeding. The goal is to determine if metformin prevents AAAs from growing larger.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Placebo
- 2.Take Metformin
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
metformin (Biguanide antidiabetic; reduces liver glucose production and improves insulin sensitivity)
oral
Secondary: All-cause mortality, Change from baseline in Living with Abdominal Aortic Aneurysm (AAA) Survey, Change from baseline in Short Form (SF-36) health survey