Study details
Enrolling now
Effects of Ketosis on Brain Function in Patients With T1DM
Boston Children's Hospital
NCT IDNCT04219709ClinicalTrials.gov data as of Apr 2026
Target enrollment
24
Study length
about 6.6 years
Ages
18–40
Locations
1 site in MA
What this study is about
This trial is testing whether a very low carbohydrate diet, which causes ketosis, affects brain function in people with type 1 diabetes. The goal is to understand how ketones protect the brain during periods of low blood sugar (hypoglycemia).
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Standard carbohydrate diet
- 2.Very low carbohydrate diet
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
Randomized (Open Label)
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Secondary: Blood glucose level at which participant reports symptoms of hypoglycemia., Hypoglycemia symptoms
Body systems
Endocrinology