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Study details
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Alpha-1 Blockade for Alcohol Use Disorder (AUD)

Brown University
NCT IDNCT04135846ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

184

Study length

about 6 years

Ages

18+

Locations

1 site in RI

What this study is about

This trial is testing whether a medication called doxazosin helps people with alcohol use disorder. Participants will receive either doxazosin or a placebo, and it will last approximately 2 years.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Doxazosin
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

doxazosin

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Alcohol consumption

Body systems

Psychiatry / Mental Health