Study details
Enrolling now
Central Sleep Apnea: Physiologic Mechanisms to Inform Treatment
VA Office of Research and Development
NCT IDNCT04118387ClinicalTrials.gov data as of Apr 2026
Phase
Phase 4
Target enrollment
200
Study length
about 6 years
Ages
18+
Locations
1 site in MI
What this study is about
This trial is testing different treatments for central sleep apnea. The goal is to find ways to improve treatment by understanding the underlying causes of central sleep apnea.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Acetazolamide + supplemental oxygen + PAP therapy
- 2.Take Buspirone + PAP therapy
- 3.Take Zolpidem + PAP therapy
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Injection / IVInjection / IV
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
acetazolamide, buspirone, zolpidem (Non-benzodiazepine hypnotic; enhances GABA to induce sleep), VARIOUS
Drug routes
injection, intravenous