Study details
Enrolling now
Nicotinic Receptor Genetic Variation and Alcohol Reward
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT IDNCT03294460ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
128
Study length
about 6.6 years
Ages
21–60
Locations
1 site in MD
What this study is about
Researchers are testing how different people react to alcohol, especially those with a nicotine receptor gene that may increase their risk of alcohol use disorder. The trial will involve healthy adults who are smokers or non-smokers, and it will investigate how variations in this gene affect brain responses to alcohol cues.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Alcohol (IV)
- 2.Take Alcohol (Ethanol)
- 3.Take Alcohol (Oral)
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Injection / IVOral
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
ethanol, DERMATOLOGICALS
Drug routes
infusion, oral