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Study details
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Vascular Function in Health and Disease

Russell Richardson
NCT IDNCT02966665ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

420

Study length

about 18 years

Ages

18+

Locations

1 site in UT

What this study is about

This trial is testing how vascular function changes with age and in people with certain diseases like COPD, heart disease, and high blood pressure. The goal is to understand why these changes happen and if they can be fixed.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Angiotensin-II, Valsartan
  • 2.Maximum Exercise Tests
  • 3.Take Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

acetylcholine, Cardiovascular Agent [TC] (Unknown Cellular or Molecular Interaction), angiotensin II, supplement (Vitamin; antioxidant), dietary supplement, fexofenadine, RESPIRATORY SYSTEM, norepinephrine

Drug routes

injection (Injection), oral (Oral Capsule), oral (Oral Tablet), ocular (Ophthalmic Solution), injection

Endpoints

Secondary: Change in Blood Pressure

Body systems

Cardiology / Heart, Respiratory